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Topical Biostimulator

PRX Topical Biostimulator in Williamsburg, VA.

No needles, no downtime — and your collagen does the work. A topical treatment that triggers renewal underneath without breaking the surface.

Starting at$1,200Series Starting at $1,200 · Three protocols below
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Estimate a monthly paymentfrom $50/mo
PRX-T33 no-needle topical treatment
Duration

30–45 minutes per session

Downtime

Minimal · mild tingling during

Results

Continue 3–6 months after last session

Frequency

Series of 4–5 · 1–2 series per year

The treatment

Collagen-building without needles.

PRX is a topical biostimulator — a layered solution applied directly to the skin (no needles, no abrasion) that penetrates without breaking the surface. Once it reaches the deeper layers, it triggers collagen and elastin renewal the same way more aggressive treatments do — just on a different timeline.

PRX is a long-game treatment, not a quick fix. Visible glow shows up within a few sessions; the real collagen-building continues for 3–6 months after the last treatment in your series. That delayed-result curve is part of why we like it for clients who want gradual improvement without disrupting their week.

Three protocols on the menu, each with a slightly different formulation focus. We'll talk through which fits in consult.

Offered at Colonial Aesthetics & Wellness, 1309 Jamestown Rd Ste 204, Williamsburg, VA, serving Yorktown, Newport News and James City County.

Real results

PRX Topical Biostimulator, before and after.

Our own patients, shown with written consent and unretouched. Individual results vary.

See Before & After Results6 skin & peels results in the gallery, with drag-to-compare.

How it works

A strong acid, without the peel.

PRX uses the same acid as a medium-depth peel, paired with an ingredient that stops it burning the surface. Compare it with a classic peel.

EPIDERMISDERMIS · COLLAGENSurface frosts, then peelsCollagen stimulatedSurface stays intact33% TCA + HYDROGEN PEROXIDESKIN SURFACE
Hydrogen peroxide buffers the acid at the surface, so it passes through intact skin to the dermis and stimulates collagen there. No frost, no peeling.

  1. Applied, never injected

    The solution is massaged into the skin. No needles, no abrasion.

  2. The surface is protected

    Hydrogen peroxide blunts the acid's effect on the outer layer, so you skip the frost and the peeling.

  3. The dermis responds

    The acid still reaches the dermis, where it signals the cells that make collagen and elastin.

  4. A weekly series

    Four or five sessions about a week apart. Glow shows early; collagen keeps building for three to six months.

  • 33%TCAWith hydrogen peroxide and kojic acid.Postepy Dermatol Alergol RCT, 2021
  • 0Frost or peelingSurface stays intact.WiQo / PRX-T33
  • 4–5SessionsAbout a week apart.Colonial Aesthetics protocol
  • 3–6 moResults keep buildingAfter the last session.Colonial Aesthetics protocol

In a randomised controlled trial on acne scars, the TCA, kojic acid and hydrogen peroxide combination worked best paired with microneedling. Diagram is illustrative. Sources: Pakla-Misiur et al., Postepy Dermatol Alergol 2021.

Protocol menu

Choose your series

Series of 4

PRX Glow

Starting at$1,200

Brightening-focused protocol. Strong on dullness, tone, and overall glow. The right starting point for most clients new to PRX.

Series of 5

PRX Plus

Starting at$1,500

Stronger collagen-building protocol with one additional session. Best for fine lines, early laxity, and skin quality.

Series of 4

PRX Plus C

Starting at$1,500

Plus formula with added vitamin C. Targeted for pigmentation, tone unevenness, and brightening alongside collagen support.

Sessions spaced 1–2 weeks apart within a series. Most clients do 1–2 series per year for ongoing improvement.

Before, during, after

What to expect.

How a PRX Topical Biostimulator visit runs, from the days before to the days after. Your provider walks you through all of it at the consultation.

  1. Before

    Come without makeup. Skip retinoids and acids for 2 days prior. No active sun exposure for a week beforehand.

  2. During

    We cleanse, then apply the PRX solution in measured layers using a specific massage technique that drives the formula into the skin. Most clients describe a mild tingling that fades over the application. Treatment is 30–45 minutes.

  3. After

    No visible downtime. Skin may feel slightly tight; this resolves within hours. Mild glow develops in the days after. SPF religiously — your skin is doing the renewal work, even if you can't see it.

Who it's for

Who it's for.

  • Clients who want skin improvement without needles or downtime
  • Pregnant clients (PRX is one of the few in-office treatments that's safe)
  • Anyone with sensitive skin who's struggled with more aggressive protocols
  • Clients building a long-term skincare investment with multiple series per year
  • Pigmentation and tone issues (PRX Plus C)

Who should hold off or check with us.

  • Active rashes, sunburn, or open lesions on the face
  • Recent aggressive in-office treatments — we'll space appropriately
  • Clients seeking immediate dramatic change — PRX is gradual

If you're unsure, ask us — we'll go through your history during your consult.

Questions clients ask us most.

Further reading

Medically reviewed by Brittany Ptachick, MSN, FNP-C and Catherine White, MSN, FNP-C

Board-certified Family Nurse Practitioners · Colonial Aesthetics & Wellness

Ready to talk through it?

Book a consultation and we'll walk through the three protocols based on your skin and goals.

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or text us at 757-585-4647

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